харакири Дельты?

[eugenegp]

На полном серьезе обсуждается гипотеза, что в Японии Дельта штамм домутировал до ̶п̶о̶л̶н̶о̶г̶о̶ ̶н̶и̶ч̶т̶о̶ж̶е̶с̶т̶в̶а̶ нежизнеспособности и самоликвидировался.

"Это очень опасно" (OMFG), ведь теперь Дельта не защищает японцев от старых штаммов.

https://www.japantimes.co.jp/news/2021/11/18/national/delta-variant-self-destruction-theory/

Comments

[eugenegp]

Текст статьи: Nov 18, 2021
Why did Japan’s fifth and biggest wave of the coronavirus pandemic, driven by the supercontagious delta variant, suddenly come to an abrupt end following a seemingly relentless rise in new infections? And what made Japan different from other developed countries that are now seeing a fresh surge in new cases?
According to one group of researchers, the surprising answer may be that the delta variant took care of itself in an act of “self-extinction.”
Three months after the delta variant spurred record daily nationwide caseloads of nearly 26,000, new COVID-19 infections in Japan have plummeted, dropping below 200 in recent weeks. Highlighting that drop was the fact that no deaths were reported on Nov. 7 — the first time that had happened in about 15 months.
Many scholars point to a variety of possibilities, which include one of the highest vaccination rates among advanced countries with 75.7% of residents fully vaccinated as of Wednesday. Other potential factors are the social distancing and mask-wearing measures that are now deeply embedded in Japanese society.
But the chief reason may be related to the genetic changes that the coronavirus undergoes during reproduction, at a pace of around two mutations per month. According to a potentially revolutionary theory proposed by Ituro Inoue, a professor at the National Institute of Genetics, the delta variant in Japan accumulated too many mutations to the virus’s error-correcting, non-structural protein called nsp14. As a result, the virus struggled to repair the errors in time, ultimately leading to “self-destruction.”
Studies have shown that more people in Asia have a defense enzyme called APOBEC3A that attacks RNA viruses, including the SARS-CoV-2 virus that causes COVID-19, when compared to people in Europe and Africa.
So the researchers from the National Institute of Genetics and Niigata University set out to discover how the APOBEC3A protein affects the nsp14 protein and whether it can inhibit the activity of the coronavirus. The team conducted an analysis of the genetic diversity data for the alpha and delta variants from infected clinical specimens in Japan from June to October.
They then visualized the relationships among the DNA sequences of the SARS-CoV-2 virus to show genetic diversity in a diagram called a haplotype network. In general, the bigger the network is, the more positive cases it represents.
The network of the alpha variant, which was the main driver for Japan’s fourth wave from March to June, had five major groups with many mutations branching out, confirming a high level of genetic diversity. The researchers thought the delta variant, which the U.S. Centers for Disease Control and Prevention says is more than twice as contagious as previous variants and might cause more severe illness in unvaccinated people, would have a far more vibrant genetic diversity.
Surprisingly, they found the opposite to be true. The haplotype network had only two major groups and the mutations seemed to come to a sudden stop in the middle of its evolutionary development process. When the researchers went on to examine the virus’s error-correcting enzyme nsp14, they discovered that the vast majority of nsp14 specimens in Japan seemed to have undergone many genetic changes in mutation sites called A394V.
“We were literally shocked to see the findings,” Inoue told The Japan Times. “The delta variant in Japan was highly transmissible and keeping other variants out. But as the mutations piled up, we believe it eventually became a faulty virus and it was unable to make copies of itself. Considering that the cases haven’t been increasing, we think that at some point during such mutations it headed straight toward its natural extinction.”
Inoue’s theory, while innovative, would lend support to the mysterious disappearance of the delta variant’s spread in Japan. While much of the rest of the world with similarly high vaccination rates, including South Korea and some Western countries, are suffering from record waves of new infections, Japan appears to be a peculiar case in that COVID-19 cases have remained subdued despite trains and restaurants filling up following the end of the most recent state of emergency.

[mikerrr]

Как писал тут некий учоный товарищ, это потому что у них у всех глисты.
Логика такая: В японии начали использовать ивермектин, он помогает только в том случае если есть глисты, а в японии как раз все едят сырую рыбу,так что ковид был побежден вместе с глистами)